Driving Breakthroughs in Type 1 Diabetes

Anastasia and Igor Bukhman have been committed supporters of Breakthrough T1D since 2015, playing a meaningful role in advancing its mission to deliver life-changing discoveries to treat, prevent, and ultimately cure type 1 diabetes (T1D). This philanthropic focus now continues through the Bukhman Foundation, reflecting a sustained dedication to empowering individuals living with T1D and supporting the pursuit of a future free from the condition.

In this context, the Foundation has made a $1 million contribution to the Breakthrough T1D Barbara Dewey Cammett Center of Excellence in New England. This funding is directed toward pioneering research in gene-edited, lab-grown insulin-producing cells, an area of innovation with transformative potential for the treatment of T1D.

The Bukhmans’ support has helped position Breakthrough T1D at the forefront of global research efforts, particularly in the development of cell-based therapies. These therapies aim to replace the insulin-producing beta cells destroyed by the immune system, offering a potential pathway to a functional cure.

In 2024, Breakthrough T1D launched Project ACT, a comprehensive initiative designed to accelerate the delivery of cell therapies to people living with T1D. The programme addresses the full development pathway, from advancing early-stage research and shaping regulatory frameworks to ensuring reimbursement, access, and healthcare system readiness. When combined with emerging therapies that aim to prevent the immune system from attacking newly introduced beta cells, these advances signal a credible and increasingly tangible path toward making T1D a condition of the past.

As Breakthrough T1D’s CEO Aaron Kowalski affirms: “As steadfast supporters of our mission, Igor and Anastasia share our vision to make T1D a condition of the past. Their partnership drives our mission forward by advancing groundbreaking research and innovative treatments that change the lives of so many in the T1D community.”

About Breakthrough T1D

Breakthrough T1D is a global leader in research and advocacy for type 1 diabetes (T1D), dedicated to enhancing the lives of those living with the condition while working towards prevention and cures. The organisation invests in cutting-edge research, collaborates with government and industry partners to improve access to care, and provides resources to empower individuals and families. By breaking barriers and driving innovation, Breakthrough T1D is transforming the future for the T1D community.